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pentobarbital will minimize the level or effect of parecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.pentobarbital will lower the level or effect of conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Observe Closely (two)pentobarbital will reduce the level or effect of olic